B.A.G. gratefully acknowledges financial support from the Camille and Henry Dreyfus New Faculty Awards Program. K.J.M.B. and C.J.C. were supported in part by the NSF-IGERT program “Dynamics of Complex Systems in Science and Engineering” (DGE-9987577).
1521-3773/asset/2002_left.gif?v=1&s=ac6b0d94a94d7ce7a210002b8096b42feffc0bcf)
1521-3773/asset/olbannercenter.gif?v=1&s=c083e1920cd41ed129901c116018eab93b5ad3c4)
1521-3773/asset/2002_right.gif?v=1&s=451042aa3415ae3ad0729984d26dee1866aca82e)
Communication
You have free access to this content
Architecture and Evolution of Organic Chemistry†
Article first published online: 8 NOV 2005
DOI: 10.1002/anie.200502272
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue
Angewandte Chemie International Edition
Volume 44, Issue 44, pages 7263–7269, November 11, 2005
Additional Information
How to Cite
Fialkowski, M., Bishop, K. J. M., Chubukov, V. A., Campbell, C. J. and Grzybowski, B. A. (2005), Architecture and Evolution of Organic Chemistry. Angew. Chem. Int. Ed., 44: 7263–7269. doi: 10.1002/anie.200502272
- †
Publication History
- Issue published online: 8 NOV 2005
- Article first published online: 8 NOV 2005
- Manuscript Revised: 31 AUG 2005
- Manuscript Received: 29 JUN 2005
Keywords:
- combinatorial chemistry;
- master equations;
- networks;
- organic reactions;
- stochastic modeling
Organic syntheses reported in the literature between 1850 and 2000 are analyzed at the simplified level of a connected network (see the picture of the network for 1850). Fundamental statistical laws that govern organic syntheses are established. These laws allow the estimation of the synthetic and industrial usefulness of organic molecules.