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Two-Component Graded Deposition of Biomolecules with a Double-Barreled Nanopipette†

  1. Kit T. Rodolfa1,
  2. Andreas Bruckbauer Dr.1,
  3. Dejian Zhou Dr.1,
  4. Yuri E. Korchev Dr.2,
  5. David Klenerman Dr.1

Article first published online: 25 OCT 2005

DOI: 10.1002/anie.200502338

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 44, Issue 42, pages 6854–6859, October 28, 2005

Additional Information

How to Cite

Rodolfa, K. T., Bruckbauer, A., Zhou, D., Korchev, Y. E. and Klenerman, D. (2005), Two-Component Graded Deposition of Biomolecules with a Double-Barreled Nanopipette. Angewandte Chemie International Edition, 44: 6854–6859. doi: 10.1002/anie.200502338

Author Information

  1. 1

    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK, Fax: (+44) 1223-336-362

  2. 2

    Division of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK

  1. †

    This work was funded by the BBSRC, and the Winston Churchill Foundation provided a studentship to K.T.R.

Publication History

  1. Issue published online: 25 OCT 2005
  2. Article first published online: 25 OCT 2005
  3. Manuscript Received: 5 JUL 2005

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Keywords:

  • DNA;
  • nanotechnology;
  • nanowriting;
  • proteins;
  • scanning probe microscopy

Graphical Abstract

Thumbnail image of graphical abstract

Pretty as a picture: The printing of highly complex graded images with two different species (see picture) has been developed through the use of double-barreled pipettes. This method of submicron deposition of biomolecules eliminates registry problems that are inherent to other deposition techniques.

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