This work was supported by the US Army Research Laboratory and the US Army Research Office under grant number DAAD19-03-1-0227, the National Science Foundation through a Science and Technology Center of Advanced Materials for Purification of Water with Systems (WaterCAMPWS), and a Nanoscale Science and Engineering Center (NSEC) program.
Fast Colorimetric Sensing of Adenosine and Cocaine Based on a General Sensor Design Involving Aptamers and Nanoparticles†
Article first published online: 17 NOV 2005
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 45, Issue 1, pages 90–94, December 16, 2005
How to Cite
Liu, J. and Lu, Y. (2006), Fast Colorimetric Sensing of Adenosine and Cocaine Based on a General Sensor Design Involving Aptamers and Nanoparticles. Angew. Chem. Int. Ed., 45: 90–94. doi: 10.1002/anie.200502589
- Issue published online: 14 DEC 2005
- Article first published online: 17 NOV 2005
- Manuscript Received: 25 JUL 2005
- DNA structures;
Apt to change color: DNA aptamers have been used to assemble DNA-functionalized gold nanoparticles to produce highly sensitive and selective colorimetric sensors with an instantaneous color response on addition of a substrate. The general method has been shown for adenosine and cocaine (see picture), but should be applicable to any aptamer of choice.