The author is indebted to the Fonds der Chemischen Industrie for a Liebig fellowship.
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Extending Mechanistic Routes in Heterazolium Catalysis–Promising Concepts for Versatile Synthetic Methods†
Article first published online: 21 NOV 2005
DOI: 10.1002/anie.200502617
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue
Angewandte Chemie International Edition
Volume 44, Issue 46, pages 7506–7510, November 25, 2005
Additional Information
How to Cite
Zeitler, K. (2005), Extending Mechanistic Routes in Heterazolium Catalysis–Promising Concepts for Versatile Synthetic Methods. Angewandte Chemie International Edition, 44: 7506–7510. doi: 10.1002/anie.200502617
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Publication History
- Issue published online: 21 NOV 2005
- Article first published online: 21 NOV 2005
- Abstract
- Article
- References
- Cited By
Keywords:
- aldehydes;
- carbenes;
- nitrogen heterocycles;
- stereoselective catalysis;
- umpolung
Graphical Abstract
A broad spectrum of valuable cyclic and acyclic products are available in diastereo- and/or enantioselective form by sustainable, organocatalytic processes like the heterazolium-catalyzed transformations shown in the scheme. The carbene-mediated generation of activated carboxylate intermediates provides new possibilities for the straightforward synthesis of multifunctionalized compounds.