Get access

Copper-in-Charcoal (Cu/C): Heterogeneous, Copper-Catalyzed Asymmetric Hydrosilylations

Authors


  • We warmly thank the NSF (CHE 0213522) for financial support, and Dr. Louise Weaver of the Microscopy and Microanalysis Facility at the University of New Brunswick for the surface analyses (http://www.unb.ca/fredericton/science/emunit/). We are also indebted to Dr. Takao Saito and Mr. Hideo Shimizu (Takasago, Co.), Drs. R. Schmid and M. Scalone (Roche, Basel), and Drs. H.-U. Blaser and M. Thommen (Solvias) for supplying the segphos, biphep, and josiphoss ligands, respectively, used in this study. We thank Ms. Danielle Nihan for providing unsaturated lactone 2.

Abstract

original image

Asymmetric copper chemistry … done heterogeneously? It's doable: Copper-in-charcoal (Cu/C) is introduced as an easily prepared catalyst that is readily converted in situ into a nonracemically ligated form of copper hydride that effects asymmetric hydrosilylations. DTBM=3,5-di-tert-butyl-4-methoxydiphenylphosphinyl.

Get access to the full text of this article

Ancillary