Communication

Neuron-Like Tubular Membranes Made of Diblock Copolymer Amphiphiles†

  1. Giuseppe Battaglia Dr.1,
  2. Anthony J. Ryan Prof.2

Article first published online: 22 FEB 2006

DOI: 10.1002/anie.200503334

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 45, Issue 13, pages 2052–2056, March 20, 2006

Additional Information

How to Cite

Battaglia, G. and Ryan, A. J. (2006), Neuron-Like Tubular Membranes Made of Diblock Copolymer Amphiphiles. Angewandte Chemie International Edition, 45: 2052–2056. doi: 10.1002/anie.200503334

Author Information

  1. 1

    Department of Engineering Materials, The Kroto Research Institute North Campus, University of Sheffield, Broad Lane, Sheffield, S3 7HQ, UK, Fax: (+44) 114-222-5945

  2. 2

    Department of Chemistry, University of Sheffield, Dainton Building, Brook Hill Sheffield, S3 7HF, UK, Fax: (+44) 114-222-9389

  1. †

    The authors thank Dr. Shao-min Mai for the synthesis of the copolymer and the ICI Strategic Technology Group for financial support.

Publication History

  1. Issue published online: 13 MAR 2006
  2. Article first published online: 22 FEB 2006
  3. Manuscript Received: 20 SEP 2005

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Keywords:

  • amphiphiles;
  • block copolymers;
  • myelins;
  • self-assembly;
  • vesicles

Graphical Abstract

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Implications for the nervous system: The formation of polymeric myelin structures was studied at the copolymer/water interface and then elaborated in a dispersed phase. Sun-like structures formed with a complex multilamellar core and a corona made of short myelins. Myelin growth is solvent-promoted, in a strong analogy to natural myelins, which have membranes with a higher proportion of fluidizing molecules such as cholesterol.

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