This research is supported by the NSF (grants CHE-0431749 and CHE-0518351). We warmly thank Dr. Seho Kim for assistance with PFG-SE NMR experiments.
One-Pot, 18-Component Synthesis of an Octahedral Nanocontainer Molecule†
Article first published online: 30 DEC 2005
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 45, Issue 6, pages 901–904, January 30, 2006
How to Cite
Liu, X., Liu, Y., Li, G. and Warmuth, R. (2006), One-Pot, 18-Component Synthesis of an Octahedral Nanocontainer Molecule. Angew. Chem. Int. Ed., 45: 901–904. doi: 10.1002/anie.200504049
- Issue published online: 23 JAN 2006
- Article first published online: 30 DEC 2005
- Manuscript Received: 15 NOV 2005
- host–guest systems;
- multicomponent reactions;
- supramolecular chemistry
A whole in one! The octahedral nanocontainer 3 composed of six cavitands 1 that are connected together by 12 diamino bridging units 2 through 24 imine bonds was synthesized in nearly quantitative yield in a one-pot reaction. Molecular mechanics calculations and NMR experiments suggest that this container has a diameter of 3.2 Å and an inner cavity volume of about 1700 Å3.