Support by Professor Paul Knochel, the DFG (Emmy Noether-Programm), the Fonds der Chemischen Industrie, and the Ludwig-Maximilians-Universität is gratefully acknowledged.
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Communication
Catalytic Arylation Reactions by C![[BOND]](http://onlinelibrarystatic.wiley.com/undisplayable_characters/00f8ff.gif)
H Bond Activation with Aryl Tosylates†
Article first published online: 17 MAR 2006
DOI: 10.1002/anie.200504450
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Ackermann, L., Althammer, A. and Born, R. (2006), Catalytic Arylation Reactions by CH Bond Activation with Aryl Tosylates. Angewandte Chemie International Edition, 45: 2619–2622. doi: 10.1002/anie.200504450
- †
Publication History
- Issue published online: 4 APR 2006
- Article first published online: 17 MAR 2006
- Manuscript Received: 14 DEC 2005
Keywords:
- CC coupling;
- CH bond activation;
- homogeneous catalysis;
- ruthenium;
- secondary phosphine oxides
Graphical Abstract
Select and direct: A ruthenium complex derived from an air-stable diaminophosphine oxide preligand allows for highly efficient and selective direct arylation reactions using aryl tosylates. The reactions proceed through CH bond activation and tolerate pronucleophiles with different directing groups, including pyrazole derivatives (see scheme; NMP=N-methylpyrrolidinone, OTs=tosylate).