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Cover Picture: CuH in a Bottle: A Convenient Reagent for Asymmetric Hydrosilylations (Angew. Chem. Int. Ed. 39/2005)
Article first published online: 30 SEP 2005
DOI: 10.1002/anie.200590130
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Lipshutz, B. H. and Frieman, B. A. (2005), Cover Picture: CuH in a Bottle: A Convenient Reagent for Asymmetric Hydrosilylations (Angew. Chem. Int. Ed. 39/2005). Angew. Chem. Int. Ed., 44: 6253. doi: 10.1002/anie.200590130
Publication History
- Issue published online: 30 SEP 2005
- Article first published online: 30 SEP 2005
Keywords:
- asymmetric synthesis;
- copper;
- hydrides;
- hydrosilylation;
- P ligands
The innate stability of the extraordinarily reactive and enantioselective reagent [{(R)-(−)-DTBM-segphos}CuH] (whose structure is shown in the cover picture) is revealed in the Communication by Lipshutz and Frieman on page 6345 ff. Although there have been many advances in ligand-accelerated catalysis of hydrosilylations, these reactions invariably require the preparation of the catalyst prior to use owing to their limited shelf-life. This new reagent represents the first asymmetric “CuH in a Bottle”.