We thank the National Science Institutes of Health (Institute for General Medical Sciences) for funding this study, the German Academic Exchange Organization (DAAD) for a fellowship (M.P.), and Prof. J. A. Marco for providing the samples.
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Communication
Solution-Phase Mixture Synthesis with Fluorous Tagging En Route: Total Synthesis of an Eight-Member Stereoisomer Library of Passifloricins†
Article first published online: 9 MAR 2006
DOI: 10.1002/anie.200600041
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Curran, D. P., Moura-Letts, G. and Pohlman, M. (2006), Solution-Phase Mixture Synthesis with Fluorous Tagging En Route: Total Synthesis of an Eight-Member Stereoisomer Library of Passifloricins. Angew. Chem. Int. Ed., 45: 2423–2426. doi: 10.1002/anie.200600041
- †
Publication History
- Issue published online: 24 MAR 2006
- Article first published online: 9 MAR 2006
- Manuscript Received: 4 JAN 2006
Keywords:
- allylation;
- asymmetric synthesis;
- fluorous tags;
- mixture synthesis;
- separation tags
Double your pleasure: A new double-tagging approach is validated by making eight individual stereoisomers of passifloricin through the intermediacy of a pair of four-compound quasi-isomeric mixtures.