J.L. gratefully acknowledges support from the NSF in form of a CAREER grant (DMR-0449462) and funding from the NSF under the MRI program (DMR-0420785). We thank Prof. Larson, University of Michigan, for use of the fluorescence microscope and Prof. J. Kim, Materials Science and Engineering, University of Michigan, for use of the spectrofluorometer.
Reactive Polymer Coatings that “Click”†
Article first published online: 19 APR 2006
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 45, Issue 20, pages 3360–3363, May 12, 2006
How to Cite
Nandivada, H., Chen, H.-Y., Bondarenko, L. and Lahann, J. (2006), Reactive Polymer Coatings that “Click”. Angew. Chem. Int. Ed., 45: 3360–3363. doi: 10.1002/anie.200600357
- Issue published online: 5 MAY 2006
- Article first published online: 19 APR 2006
- Manuscript Received: 26 JAN 2006
- chemical vapor deposition;
- click chemistry;
- reactive coatings
Everything just clicks into place: Alkyne-group functionalized polymer films that are deposited from the gas phase allow spatially defined immobilization of biomolecules, such as biotin, through the 1,3-dipolar cycloaddition click reaction with azide derivatives (see scheme). Such biofunctional surfaces have applications in diagnostics and biosensors.