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The Heck Reaction of Electron-Rich Olefins with Regiocontrol by Hydrogen-Bond Donors



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No salt please: Halide scavengers AgOTf and TlOAc are not required for the Heck coupling of electron-rich olefins with aryl bromides and chlorides. Using ammonium additives, these reactions can be carried out in either an imidazolium ionic liquid or a common molecular solvent, thus furnishing 1,1′-disubstituted olefins in high yields with excellent regioselectivities.