Communication

Colloidal Crystal Beads as Supports for Biomolecular Screening†

  1. Xiangwei Zhao1,2,
  2. Yun Cao1,
  3. Fuyumi Ito Dr.3,
  4. Hai-Hua Chen1,
  5. Keiji Nagai Dr.3,
  6. Yu-Hua Zhao Prof.2,
  7. Zhong-Ze Gu Prof. Dr.1

Article first published online: 26 SEP 2006

DOI: 10.1002/anie.200601302

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 45, Issue 41, pages 6835–6838, October 20, 2006

Additional Information

How to Cite

Zhao, X., Cao, Y., Ito, F., Chen, H.-H., Nagai, K., Zhao, Y.-H. and Gu, Z.-Z. (2006), Colloidal Crystal Beads as Supports for Biomolecular Screening. Angewandte Chemie International Edition, 45: 6835–6838. doi: 10.1002/anie.200601302

Author Information

  1. 1

    State Key Laboratory of Bioelectronics, Southeast University, Nanjing 210096, China, Fax: (+86) 25-8379-5635

  2. 2

    College of Life Science, Zhejiang University, Hangzhou 310029, China

  3. 3

    Institute of Laser Engineering (ILE), Osaka University, Osaka 565-0871, Japan

  1. †

    This work was supported by the National Natural Science Foundation (grants 20573018 and 60121101).

Publication History

  1. Issue published online: 17 OCT 2006
  2. Article first published online: 26 SEP 2006
  3. Manuscript Revised: 5 AUG 2006
  4. Manuscript Received: 3 APR 2006

Funded by

  • National Natural Science Foundation. Grant Numbers: 20573018, 60121101

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Keywords:

  • colloids;
  • high-throughput screening;
  • immunoassays;
  • nanoparticles;
  • self-assembly

Graphical Abstract

Thumbnail image of graphical abstract

Crystal balls: Colloidal crystal microbeads with a three-dimensional photonic crystal structure can be fabricated with a droplet generator and their reflection spectra used as encoding elements. A multiplex bioassay demonstrates their reliability as encoded carriers (see picture: red, green, and blue beads are immobilized with human, mouse, and rabbit immunoglobulin, respectively).

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