A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide


  • We thank the ETH Zurich and the University of Zurich for financial support and Joris Beld for operating the analytical ultracentrifuge.


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Flip a switch: A peptide capable of adopting different conformations is constructed upon insertion of an azobenzene linker into the polypeptide backbone. A simple transformation (irradiation or heating) can be used to switch from one form to the other.