The authors acknowledge the financial support from an NIH AREA award 1R15 GM066279-01A2.
A General Approach to the Covalent Immobilization of Single Polymers†
Article first published online: 14 AUG 2006
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 45, Issue 37, pages 6207–6210, September 18, 2006
How to Cite
Liu, L. and Yan, M. (2006), A General Approach to the Covalent Immobilization of Single Polymers. Angew. Chem. Int. Ed., 45: 6207–6210. doi: 10.1002/anie.200602097
- Issue published online: 11 SEP 2006
- Article first published online: 14 AUG 2006
- Manuscript Received: 25 MAY 2006
- NIH. Grant Number: 1R15 GM066279-01A2
- scanning probe microscopy;
- single-molecule studies
Stuck fast: The covalent immobilization of polymeric single molecules is achieved by the photochemically induced CH/NH insertion reaction of perfluorophenylazides (see picture). When the concentration of the surface azido groups is decreased, isolated polymeric single molecules are observed. This technique is especially suited for materials that do not possess functional groups and are difficult to be immobilized by other means.