Diastereoselective Gold-Catalyzed Cycloisomerizations of Ene-Ynamides

Authors


  • Financial support from Johnson & Johnson (Focus Giving Award to J.C.) is gratefully acknowledged.

Abstract

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Around they go: 1,6-Ene-ynamides undergo highly diastereoselective gold-catalyzed cycloisomerizations that lead to functionalized cyclobutanones or carbonyl compounds with a 2-azabicyclo[3.1.0]hexane subunit, depending on the substitution pattern (Ts=p-toluenesulfonyl).

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