This work was supported financially by the National Natural Science Foundation of China (Nos. 20574077, 20471063, 20403022, and 90206035) and the Chinese Academy of Sciences, as well as the German Max Planck Society collaboration project. The authors acknowledge Hans Riegler for critical reading of the manuscript.
Transition of Cationic Dipeptide Nanotubes into Vesicles and Oligonucleotide Delivery†
Article first published online: 28 FEB 2007
Copyright © 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 46, Issue 14, pages 2431–2434, March 26, 2007
How to Cite
Yan, X., He, Q., Wang, K., Duan, L., Cui, Y. and Li, J. (2007), Transition of Cationic Dipeptide Nanotubes into Vesicles and Oligonucleotide Delivery. Angew. Chem. Int. Ed., 46: 2431–2434. doi: 10.1002/anie.200603387
- Issue published online: 16 MAR 2007
- Article first published online: 28 FEB 2007
- Manuscript Received: 18 AUG 2006
- National Natural Science Foundation of China. Grant Numbers: 20574077, 20471063, 20403022, 90206035
- Chinese Academy of Sciences
- Max Planck Society
- peptide nanotubes;
Password?—Vesicle! A cationic dipeptide can self-assemble into nanotubes at physiological pH values. Such self-assembled cationic dipeptide nanotubes (CDPNTs) are able to convert into vesicles spontaneously upon dispersion dilution and thus carry single-stranded DNA into HeLa cells across the biomembrane (see picture).