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Keywords:

  • cells;
  • oligonucleotides;
  • peptide nanotubes;
  • self-assembly;
  • vesicles
Thumbnail image of graphical abstract

Password?—Vesicle! A cationic dipeptide can self-assemble into nanotubes at physiological pH values. Such self-assembled cationic dipeptide nanotubes (CDPNTs) are able to convert into vesicles spontaneously upon dispersion dilution and thus carry single-stranded DNA into HeLa cells across the biomembrane (see picture).