Controlled Release of Guest Molecules from Mesoporous Silica Particles Based on a pH-Responsive Polypseudorotaxane Motif

Authors

  • Chiyoung Park,

    1. Department of Polymer Science and Engineering, Hyperstructured Organic Materials Research Center, Inha University, Incheon 402-751, South Korea, Fax: (+82) 32-865-5178
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  • Kyoungho Oh,

    1. Department of Polymer Science and Engineering, Hyperstructured Organic Materials Research Center, Inha University, Incheon 402-751, South Korea, Fax: (+82) 32-865-5178
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  • Sang Cheon Lee Dr.,

    1. Nanomaterials Application Division, Korea Institute of Ceramic Engineering and Technology, Seoul 153-801, South Korea
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  • Chulhee Kim Prof.

    1. Department of Polymer Science and Engineering, Hyperstructured Organic Materials Research Center, Inha University, Incheon 402-751, South Korea, Fax: (+82) 32-865-5178
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  • This work was supported by the Korea Research Foundation (KRF-2005-041-D00238). C.K. also thanks the HOMRC for support.

Abstract

original image

Stringing them along: The pores of a mesoporous silica particle were filled with guest molecules and then blocked by threading cyclodextrin molecules (CDs) onto the surface-grafted polyethylenimine (PEI) chains at pH 11. At pH 5.5, the guest molecules can be released from the pores of the particle by reversible dethreading of the CDs from the PEI chains.

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