Communication

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays†

  1. Andres W. Martinez,
  2. Scott T. Phillips Dr.,
  3. Manish J. Butte Dr.,
  4. George M. Whitesides Prof.

Article first published online: 9 JAN 2007

DOI: 10.1002/anie.200603817

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 46, Issue 8, pages 1318–1320, February 12, 2007

Additional Information

How to Cite

Martinez, Andres W., Phillips, Scott T., Butte, Manish J. and Whitesides, George M. (2007), Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays. Angew. Chem. Int. Ed., 46: 1318–1320. doi: 10.1002/anie.200603817

Author Information

  1. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA, Fax: (+1) 617-495-9857

  1. †

    This research was supported by the National Institutes of Health (NIH) (GM065364). We used the Materials Research Science and Engineering Centers (MRSEC) shared facilities supported by the National Science Foundation (NSF) under award number DMR-0213805. This work also was supported by a predoctoral fellowship from NSF (A.W.M), a Damon Runyon Cancer Research Foundation Fellowship (DRG-1805-04) (S.T.P), and an Alexander and Margaret Stewart Trust Award and Massachusetts Technology Transfer Council Grant (M.J.B.).

Publication History

  1. Issue published online: 5 FEB 2007
  2. Article first published online: 9 JAN 2007
  3. Manuscript Received: 16 SEP 2006

Funded by

  • National Institutes of Health (NIH). Grant Number: GM065364
  • Materials Research Science and Engineering Centers (MRSEC)
  • National Science Foundation (NSF). Grant Number: DMR-0213805

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Keywords:

  • analytical methods;
  • bioassays;
  • clinical chemistry;
  • lithography;
  • trace analysis
Thumbnail image of graphical abstract

By the book: A method for patterning paper with photoresist to create well-defined, millimeter-sized channels comprising hydrophilic paper bounded by hydrophobic polymer is described. This type of patterned paper is a prototype of a class of low-cost, portable, and technically simple platforms for running multiplexed bioassays with microliter volumes of a single biological sample.

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