SEARCH

SEARCH BY CITATION

Keywords:

  • cyclization;
  • domino reactions;
  • gold;
  • homogeneous catalysis;
  • rearrangement
Thumbnail image of graphical abstract

Au-spicious! Under silver-free conditions, simple 3-silyloxy-1,5-enynes were converted into complex cyclopentenes by a gold(I)-catalyzed sequence that likely proceeds through a carbocyclization followed by a pinacol rearrangement. For the final demetalation step, isopropyl alcohol and N-iodosuccinimide are effectively utilized, and the resulting products are set up for a wealth of further reactions.