Bioceramic Macrocapsules for Cell Immunoisolation

Authors

  • Shaomin Liu Dr.,

    1. ARC Centre for Functional Nanomaterials, School of Engineering and Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Queensland 4072, Australia, Fax: (+61) 733-656-074
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  • Lihong Liu Dr.,

    1. Institute of Bioengineering and Nanotechnology, 31 Biopolis, The Nanos, Singapore 138669, Singapore
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  • Zhi Ping Xu Dr.,

    1. ARC Centre for Functional Nanomaterials, School of Engineering and Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Queensland 4072, Australia, Fax: (+61) 733-656-074
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  • Aimin Yu Dr.,

    1. ARC Centre for Functional Nanomaterials, School of Engineering and Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Queensland 4072, Australia, Fax: (+61) 733-656-074
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  • Gao Qing Lu Prof.,

    1. ARC Centre for Functional Nanomaterials, School of Engineering and Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Queensland 4072, Australia, Fax: (+61) 733-656-074
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  • Joao C. Diniz da Costa Dr.

    1. ARC Centre for Functional Nanomaterials, School of Engineering and Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Queensland 4072, Australia, Fax: (+61) 733-656-074
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  • The authors acknowledge the financial support from the ARC Centre for Functional Nanomaterials funded by the Australia Research Council under its Centre of Excellence Scheme. The authors wish to express sincere gratitude to Dr. Peilin Mao, Yuanhong Yu, and Dr. Xigeng Miao for their valuable suggestions and assistance.

Abstract

original image

A bone to pick: Tailor-made zirconia macrocapsules are biocompatible and friendly to MC3T3-E1 cells and can facilitate osteoblast cell differentiation. Cells encapsulated within such capsular chambers are viable and grow well by absorbing the nutrients permeated through the capsule micropores from the outside environment. These capsules are promising as immunoisolation medical templates for bone-tissue engineering.

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