SEARCH

SEARCH BY CITATION

Keywords:

  • alkynes;
  • biotransformation;
  • enzyme catalysis;
  • green chemistry;
  • reduction
Thumbnail image of graphical abstract

Old enzyme, new trick: An environmentally sustainable alternative for the regio- and stereoselective reduction of the alkyne bond is the biotransformation by “Old Yellow Enzyme” (OYE). This “old” enzyme, first isolated in 1932, catalyzes the trans-selective hydrogenation of the carbon–carbon triple bond under mild conditions.