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“Intelligent” Fingerprinting: Simultaneous Identification of Drug Metabolites and Individuals by Using Antibody-Functionalized Nanoparticles†

  1. Richard Leggett1,
  2. Emma E. Lee-Smith1,
  3. Sue M. Jickells Dr.2,
  4. David A. Russell Prof.1

Article first published online: 27 APR 2007

DOI: 10.1002/anie.200700217

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 46, Issue 22, pages 4100–4103, May 25, 2007

Additional Information

How to Cite

Leggett, R., Lee-Smith, Emma E., Jickells, Sue M. and Russell, David A. (2007), “Intelligent” Fingerprinting: Simultaneous Identification of Drug Metabolites and Individuals by Using Antibody-Functionalized Nanoparticles. Angew. Chem. Int. Ed., 46: 4100–4103. doi: 10.1002/anie.200700217

Author Information

  1. 1

    School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, Norfolk, NR4 7TJ, UK, Fax: (+44) 1603-593-012

  2. 2

    Department of Forensic Science and Drug Monitoring, King's College London, Franklin-Wilkin's Building, 150 Stamford Street, London, SE1 9NH, UK

  1. †

    This work was supported by the EPSRC (grant EP/D041007/1 and grant EP/D041082/1 for D.A.R. and S.M.J., respectively).

Publication History

  1. Issue published online: 16 MAY 2007
  2. Article first published online: 27 APR 2007
  3. Manuscript Revised: 26 MAR 2007
  4. Manuscript Received: 16 JAN 2007

Funded by

  • EPSRC. Grant Numbers: EP/D041007/1, EP/D041082/1

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Keywords:

  • antibodies;
  • biosensors;
  • diagnostics;
  • fluorescence detection;
  • nanomaterials
Thumbnail image of graphical abstract

Thumbs up: A method of fingerprinting that enables both identification of an individual and simultaneous determination of the chemical makeup of the sweat deposited in the fingerprint has been determined. Potential applications of this methodology are enormous as the functionalization of nanoparticles with other antibodies enables the specific detection of numerous antigens within a fingerprint.

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