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Keywords:

  • analytical methods;
  • DNA replication;
  • microreactors;
  • molecular biology;
  • polymerase chain reaction
Thumbnail image of graphical abstract

Is that a PCR in your pocket? An innovative thermocycling system is presented that harnesses natural convection to perform rapid multiplex and long-target DNA amplification by the polymerase chain reaction (PCR). The design is inherently simple and consumes minimal electrical power, enabling a pocket-sized battery-powered device to be constructed at a cost of approximately US$10.