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Keywords:

  • anhydrides;
  • lanthanum;
  • phosphinylimines;
  • silanes;
  • synthetic methods
Thumbnail image of graphical abstract

Hydrated lanthanum triflate has been shown to be an effective and highly active Lewis acid catalyst for nucleophilic addition to N-phosphinylimines in the presence of trifluoroacetic anhydride (TFAA; see scheme). Unexpectedly, trifluoroacetamide products are produced in a novel process which likely involves consecutive acylation/hydration of N-phosphinylimine substrates and subsequent nucleophilic addition.