Silver-Catalyzed Intermolecular Amination of C[BOND]H Groups


  • This research was supported by the University of Chicago and a Research Fellowship from the Alfred P. Sloan Foundation (C.H.)


original image

Teamwork: The dinuclear silver complex [Ag2(OTf)2(bp)2] (OTf=trifluoromethanesulfonate, bp=bathophenanthroline) catalyzes the intermolecular amination of saturated C[BOND]H bonds by using PhI[DOUBLE BOND]NNs (Ns=p-nitrosulfonyl) as the nitrene precursor (see scheme). Preliminary investigations suggest that the dinuclear structural motif is crucial to catalytic performance.