An R-Selective Hydroxynitrile Lyase from Arabidopsis thaliana with an α/β-Hydrolase Fold


  • The authors thank the group of Ute Höcker (University of Düsseldorf, Botanik IV) for providing Arabidopsis cDNA and mRNA.


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Folding and selectivity: The noncyanogenic plant Arabidopsis thaliana contains a new hydroxynitrile lyase, which was cloned and characterized. This enzyme is readily available form a recombinant source, has a broad range of substrates, and enantioselectively transforms aliphatic and aromatic aldehydes as well as ketones into the corresponding R-cyanohydrins.