Contribution of a Solute's Chiral Solvent Imprint to Optical Rotation


  • This work was supported by Duke University and the University of Pittsburgh. P.M. gratefully acknowledges the national “Grant in Aid of Research” by Sigma Xi.


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Solvent or solute dissymmetry? The dissymmetric ordering of solvent molecules around the chiral solute (see picture) contributes to the chiroptical signature. Indeed, the solvent can dominate the chiroptical response, as shown for (S)-methyloxirane in benzene.