This work was supported by a Swiss National Science Foundation fellowship to R.F., a U.S. NSF Fellowship to M.M.C. and by the U.S. Army Research Office, ARO Contract DAAD19-03-D-0004. We thank Dr. Christopher Snow for providing the homology model of P450BM3 reductase and Dr. Matthew W. Peters, Dr. Peter Meihnold, and Dr. Marco Landwehr for helpful discussions regarding the biotransformations and for providing access to DasGip fermenter.
Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties†
Article first published online: 20 SEP 2007
Copyright © 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 46, Issue 44, pages 8414–8418, November 12, 2007
How to Cite
Fasan, R., Chen, Mike M., Crook, Nathan C. and Arnold, Frances H. (2007), Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties. Angew. Chem. Int. Ed., 46: 8414–8418. doi: 10.1002/anie.200702616
- Issue published online: 2 NOV 2007
- Article first published online: 20 SEP 2007
- Manuscript Received: 15 JUN 2007
- Swiss National Science Foundation
- U.S. NSF
- U.S. Army Research Office. Grant Number: DAAD19-03-D-0004
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