Quantum Dot Bioconjugation during Core–Shell Synthesis


  • This research was partly supported by grants from the NSF, NIH, AFOSR, and ONR and grants from Arizona State University to H.Y.


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One small step: A facile and robust one-step method for creating stable, water-soluble quantum dot (QD)–biomolecule conjugates is described. DNA molecules can be readily attached to QDs during core–shell synthesis (see picture of DNA functionalization of a CdSe@ZnS core–shell QD).