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Keywords:

  • aptamers;
  • DNA;
  • nanoparticles;
  • nanostructures;
  • self-assembly
Thumbnail image of graphical abstract

The biomachinery of rolling-circle amplification relying on protein–aptamer interactions on DNA scaffolds was used to create one-dimensional DNA–protein/DNA–protein–nanoparticle hierarchical assemblies. These conjugates can serve as further templates for the immobilization of gold nanoparticles.