Catalytic Asymmetric Boration of Acyclic α,β-Unsaturated Esters and Nitriles


  • This work was supported by the Faculty Research Fund 2005, Sungkyunkwan University. We thank Solvias for supplying the ligands used in this study.


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Asymmetric β-boration of acyclic α,β-unsaturated carbonyl compounds provides ready access to enantioenriched functionalized organoboron compounds. A range of acyclic unsaturated esters and nitriles reacted with high enantioselectivity and good yields at room temperature using a copper catalyst and planar chiral diphosphine ligands (L).