The Catalytic Asymmetric Strecker Reaction: Ketimines Continue to Join the Fold

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Abstract

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Picking up the gauntlet: The challenge of developing highly effective catalyst systems for the enantioselective Strecker reaction to convert ketimine substrates (see scheme, red; A denotes protecting group) into α-amino nitriles (blue) and ultimately α-amino acids has been met by several recent developments.

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