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Electrically Addressable Cell Immobilization Using Phenylboronic Acid Diazonium Salts


  • Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy under contract DE-AC04-94AL8500.


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Holding cells: Individual gold electrodes can be activated by phenylboronic acid diazonium salts for the facile and reversible immobilization of eukaryotic cells (see scheme). This platform provides a simple method for on-demand release of captured cells (yeast and macrophage) and can be used in single-cell or array-based studies.

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