The authors gratefully acknowledge Dr. Brandon T. Ruotolo, Dr. Justin L. P. Benesch, and Prof. Carol V. Robinson for the mass spectrometry analysis. This work was supported by the EPSRC and the RCUK Basic Technology Programme.
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Communication
From Microdroplets to Microfluidics: Selective Emulsion Separation in Microfluidic Devices†
Article first published online: 8 FEB 2008
DOI: 10.1002/anie.200704903
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue
Angewandte Chemie International Edition
Volume 47, Issue 11, pages 2042–2045, February 28, 2008
Additional Information
How to Cite
Fidalgo, Luis M., Whyte, G., Bratton, D., Kaminski, Clemens F., Abell, C. and Huck, Wilhelm T. S. (2008), From Microdroplets to Microfluidics: Selective Emulsion Separation in Microfluidic Devices. Angew. Chem. Int. Ed., 47: 2042–2045. doi: 10.1002/anie.200704903
- †
Publication History
- Issue published online: 22 FEB 2008
- Article first published online: 8 FEB 2008
- Manuscript Received: 23 OCT 2007
Funded by
- EPSRC
- RCUK Basic Technology Programme
Keywords:
- electrocoalescence;
- high-throughput screening;
- microdroplets;
- microfluidics
The contents of microdroplets can be extracted on-chip and incorporated by electrocoalescence into a continuous microfluidic stream. Individual droplets can be selected based on their contents. As a proof of principle, a fluorescence detection system was used to collect droplets containing low levels of a fluorescent dye (see picture of droplets passing through the device) as well as single fluorescent beads.