SEARCH

SEARCH BY CITATION

Keywords:

  • cross-coupling;
  • homogeneous catalysis;
  • molecular oxygen;
  • palladium;
  • reaction mechanisms
Thumbnail image of graphical abstract

An oxidation exercise: An aerobic alcohol oxidation coupled with a regioselective palladium-catalyzed reductive functionalization of styrenes and arylboronic esters has been developed (see scheme). The mechanism is thought to proceed by initial oxidation of the solvent to generate a PdII-hydride species, which subsequently reacts with the alkene and arylboronic ester to ultimately generate a new C[BOND]C bond.