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Keywords:

  • aluminum;
  • natural products;
  • quinine;
  • reduction
Thumbnail image of graphical abstract

Put to rest: The three-step conversion of d-quinotoxine into quinine, as originally reported by Rabe and Kindler in 1918, has been experimentally verified. This conversion serves to reaffirm the formal total synthesis of quinine reported by Woodward and Doering in 1944.