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Keywords:

  • annulation;
  • heterocycles;
  • morpholines;
  • vinyl sulfonium salts;
  • ylides
Thumbnail image of graphical abstract

Heterocycling: Diphenyl vinyl sulfonium salt 1 acts first as an electrophile, then a base, and then again as an electrophile in this operationally simple, high yielding, one-pot synthesis of pharmacologically important morpholines, thiomorpholines, and piperazines. Compound 1 is an excellent synthon for the 1,2-ethane dication.