This work was supported by grants from the National R&D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea (S.J., M.Y., J.P., and Y.J.; 0720210 and 0520080-1). We also thank Prof. B. K. Cho at GIST for the magnetization measurement.
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Communication
Drug-Loaded Superparamagnetic Iron Oxide Nanoparticles for Combined Cancer Imaging and Therapy In Vivo†
Article first published online: 12 JUN 2008
DOI: 10.1002/anie.200800857
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Yu, M., Jeong, Y., Park, J., Park, S., Kim, J., Min, J., Kim, K. and Jon, S. (2008), Drug-Loaded Superparamagnetic Iron Oxide Nanoparticles for Combined Cancer Imaging and Therapy In Vivo. Angew. Chem. Int. Ed., 47: 5362–5365. doi: 10.1002/anie.200800857
- †
Publication History
- Issue published online: 7 JUL 2008
- Article first published online: 12 JUN 2008
- Manuscript Revised: 9 MAY 2008
- Manuscript Received: 21 FEB 2008
Funded by
- Ministry of Health and Welfare, Republic of Korea. Grant Numbers: 0720210, 0520080-1
Keywords:
- antitumor agents;
- drug delivery;
- imaging agents;
- nanotechnology
Multitasking rust ball: The questions of where a tumor is located, whether drugs are properly delivered to the tumor, and what the therapeutic response of the tumor is, could be answered by using simple but smart, drug-loaded superparamagnetic iron oxide nanoparticles that can accumulate in tumor with high efficiency thanks to the presence of rationally engineered polymer coating layers.