Drug-Loaded Superparamagnetic Iron Oxide Nanoparticles for Combined Cancer Imaging and Therapy In Vivo


  • This work was supported by grants from the National R&D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea (S.J., M.Y., J.P., and Y.J.; 0720210 and 0520080-1). We also thank Prof. B. K. Cho at GIST for the magnetization measurement.


original image

Multitasking rust ball: The questions of where a tumor is located, whether drugs are properly delivered to the tumor, and what the therapeutic response of the tumor is, could be answered by using simple but smart, drug-loaded superparamagnetic iron oxide nanoparticles that can accumulate in tumor with high efficiency thanks to the presence of rationally engineered polymer coating layers.