We are grateful to S. Stevanovic and C. Henkel for MALDI measurements, J. Bernhagen for help in establishing the insulin receptor assays, and L. M. Yan for helpful discussions and preliminary studies on insulin fibrillization. This work was supported by the Deutsche Forschungsgemeinschaft (DFG).
Exploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic†
Article first published online: 8 AUG 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 47, Issue 37, pages 7114–7118, September 1, 2008
How to Cite
Velkova, A., Tatarek-Nossol, M., Andreetto, E. and Kapurniotu, A. (2008), Exploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic. Angew. Chem. Int. Ed., 47: 7114–7118. doi: 10.1002/anie.200801499
- Issue published online: 27 AUG 2008
- Article first published online: 8 AUG 2008
- Manuscript Revised: 11 JUN 2008
- Manuscript Received: 30 MAR 2008
- Deutsche Forschungsgemeinschaft
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