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Keywords:

  • antibiotics;
  • biomaterials;
  • conjugates;
  • natural products;
  • siderophores
Thumbnail image of graphical abstract

The power of two! A natural product hybrid (see structure) composed of a siderophore and an antibiotic separated by a poly(ethylene glycol) linker enables the preparation of antimicrobial and cell-resistant surfaces by a simple dip-and-rinse procedure. The anachelin siderophore (left) binds strongly to TiO2 surfaces, and vancomycin is responsible for antibiotic activity.