Carboxylation of Organoboronic Esters Catalyzed by N-Heterocyclic Carbene Copper(I) Complexes


  • This work was partly supported by a Grant-in-aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan. We thank Mrs. Hu (RIKEN) for elemental analysis.


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Copper complexes with a CO2fixation: Copper(I) complexes serve as excellent catalysts for the carboxylation of aryl- and alkenylboronic esters with CO2, affording a variety of functionalized carboxylic acid derivatives (see scheme). Important active intermediates such as the copper(I) aryl and carboxylate complexes, [(IPr)CuR] and [(IPr)CuOCOR] (R=4-MeOC6H4, IPr=1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene), are isolated and structurally characterized.