This work was partly supported by a Grant-in-aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan. We thank Mrs. Hu (RIKEN) for elemental analysis.
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Communication
Carboxylation of Organoboronic Esters Catalyzed by N-Heterocyclic Carbene Copper(I) Complexes †
Article first published online: 24 JUN 2008
DOI: 10.1002/anie.200801857
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Ohishi, T., Nishiura, M. and Hou, Z. (2008), Carboxylation of Organoboronic Esters Catalyzed by N-Heterocyclic Carbene Copper(I) Complexes . Angewandte Chemie International Edition, 47: 5792–5795. doi: 10.1002/anie.200801857
- †
Publication History
- Issue published online: 14 JUL 2008
- Article first published online: 24 JUN 2008
- Manuscript Received: 21 APR 2008
Funded by
- Ministry of Education, Culture, Sports, Science and Technology of Japan
Keywords:
- boronic esters;
- carbene ligands;
- carbon dioxide;
- carboxylation;
- copper catalysts
Graphical Abstract
Copper complexes with a CO2fixation: Copper(I) complexes serve as excellent catalysts for the carboxylation of aryl- and alkenylboronic esters with CO2, affording a variety of functionalized carboxylic acid derivatives (see scheme). Important active intermediates such as the copper(I) aryl and carboxylate complexes, [(IPr)CuR] and [(IPr)CuOCOR] (R=4-MeOC6H4, IPr=1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene), are isolated and structurally characterized.