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This work was supported in part by a Grant-in-Aid for Scientific Research on Priority Areas (No. 18033055 “Chemistry of Coordination Space”) from the Ministry of Education, Science, Sports, and Culture (Japan).
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Asymmetric Suzuki–Miyaura Coupling Reactions Catalyzed by Chiral Palladium Nanoparticles at Room Temperature†
Article first published online: 1 AUG 2008
DOI: 10.1002/anie.200802174
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Sawai, K., Tatumi, R., Nakahodo, T. and Fujihara, H. (2008), Asymmetric Suzuki–Miyaura Coupling Reactions Catalyzed by Chiral Palladium Nanoparticles at Room Temperature. Angew. Chem. Int. Ed., 47: 6917–6919. doi: 10.1002/anie.200802174
- †
Publication History
- Issue published online: 20 AUG 2008
- Article first published online: 1 AUG 2008
- Manuscript Received: 9 MAY 2008
Funded by
- Ministry of Education, Science, Sports, and Culture (Japan). Grant Number: 18033055
Keywords:
- asymmetric catalysis;
- cross-coupling;
- nanostructures;
- P ligands;
- palladium
Similar but different: Chiral mono- and bisphosphine ligands have been used to prepare chiral stabilized palladium nanoparticles (Pd NPs). Despite the chiral Pd NPs having similar diameters of 1.2–1.7 nm, they show very different catalytic activities and enantioselectivities in the room-temperature asymmetric Suzuki–Miyaura cross-coupling reactions of aryl halides with aryl boronic acids (see picture).