Communication

Enzymatic Synthesis of Multiple Spin-Labeled DNA†

  1. Samra Obeid1,
  2. Maxim Yulikov Dr.1,2,
  3. Gunnar Jeschke Prof. Dr.1,2,
  4. Andreas Marx Prof. Dr.1

Article first published online: 31 JUL 2008

DOI: 10.1002/anie.200802314

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 47, Issue 36, pages 6782–6785, August 25, 2008

Additional Information

How to Cite

Obeid, S., Yulikov, M., Jeschke, G. and Marx, A. (2008), Enzymatic Synthesis of Multiple Spin-Labeled DNA. Angew. Chem. Int. Ed., 47: 6782–6785. doi: 10.1002/anie.200802314

Author Information

  1. 1

    Department of Chemistry and Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstrasse 10, 78457 Konstanz (Germany), Fax: (+49) 7531-88-5140

  2. 2

    Present address: Department of Chemistry, ETH Zurich, 8093 Zurich (Switzerland).

  1. †

    We gratefully acknowledge funding by the DFG.

Publication History

  1. Issue published online: 20 AUG 2008
  2. Article first published online: 31 JUL 2008
  3. Manuscript Received: 17 MAY 2008

Funded by

  • DFG

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Keywords:

  • DNA polymerase;
  • DNA;
  • EPR spectroscopy;
  • nucleotides;
  • spin labels
Thumbnail image of graphical abstract

Multi-spinning: The use of modified triphosphates and DNA polymerases has resulted in the multiple spin-labeling of DNA (see picture). A DNA helix entirely labeled with paramagnetic centers has been generated in this way and investigated by EPR spectroscopy.

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