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Keywords:

  • contrast agents;
  • drug delivery;
  • magnetic resonance imaging;
  • manganese;
  • nanoparticles
Thumbnail image of graphical abstract

MRI jack-o'-lanterns? Hollow manganese oxide nanoparticles (HMON) show greatly improved relaxivities and drug-loading capacities compared to those with solid interiors (WMON). Their efficient cellular uptake demonstrates their potential as a bifunctional medical system that combines diagnostic imaging and targeted therapy.