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Keywords:

  • azo compounds;
  • C[BOND]F activation;
  • hydrazones;
  • nitrogen heterocycles;
  • tetrazoles
Thumbnail image of graphical abstract

N&Ns: The C[BOND]F bond of trifluoromethylazoalkanes, in the presence of a hydrogen at the α carbon, is activated under basic conditions to form a difluoromethylene intermediate with a conjugated double bond, which is transformed in good yield to the corresponding 5-azido-(1-dialkylimino)tetrazole by reaction with NaN3.