Communication

Reactive Intermediates in Oxygenation Reactions with Mononuclear Nonheme Iron Catalysts†

  1. Jihae Yoon1,
  2. Samuel A. Wilson2,
  3. Yu Kyeong Jang1,
  4. Mi Sook Seo Dr.1,
  5. Kasi Nehru1,
  6. Britt Hedman2,
  7. Keith O. Hodgson Prof. Dr.2,
  8. Eckhard Bill Dr.3,
  9. Edward I. Solomon Prof. Dr.2,
  10. Wonwoo Nam Prof. Dr.1

Article first published online: 9 JAN 2009

DOI: 10.1002/anie.200802672

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 48, Issue 7, pages 1257–1260, February 2, 2009

Additional Information

How to Cite

Yoon, J., Wilson, Samuel A., Jang, Y., Seo, M., Nehru, K., Hedman, B., Hodgson, Keith O., Bill, E., Solomon, Edward I. and Nam, W. (2009), Reactive Intermediates in Oxygenation Reactions with Mononuclear Nonheme Iron Catalysts. Angew. Chem. Int. Ed., 48: 1257–1260. doi: 10.1002/anie.200802672

Author Information

  1. 1

    Department of Chemistry and Nano Science, Department of Bioinspired Science, Ewha Womans University, Seoul 120–750 (Korea), Fax: (+82) 2-3277-4441

  2. 2

    Department of Chemistry, Stanford University (USA)

  3. 3

    Max-Planck-Institut für Bioanorganische Chemie, Mülheim (Germany)

  1. †

    The research at EWU was supported by KOSEF/MOST through the CRI Program and the WCU project, Korea, and that at Stanford University by NIH grants RR-01209 (K.O.H.) and GM 40392 (E.I.S.). SSRL operations is funded by the US DOE BES, and the SSRL SMB program by NIH NCRR BTP and DOE BER. The project described was supported by grant no. 5 P41 RR001209 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and its contents are solely the responsibility of the authors and do not necessarily represent the official view of the NCRR or the NIH.

Publication History

  1. Issue published online: 28 JAN 2009
  2. Article first published online: 9 JAN 2009
  3. Manuscript Revised: 19 NOV 2008
  4. Manuscript Received: 6 JUN 2008

Funded by

  • KOSEF/MOST
  • NIH. Grant Numbers: RR-01209, GM 40392
  • US DOE BES

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Keywords:

  • bioinorganic chemistry;
  • C[BOND]H activation;
  • enzyme models;
  • iron;
  • oxidation

Abstract

Thumbnail image of graphical abstract

An advanced intermediate: A nonheme iron(IV) oxo complex [FeIV(O)(bqen)(L)]n+ (bqen=N,N′-dimethyl-N,N′-bis(8-quinolyl)ethane-1,2-diamine, L=CH3CN or CF3SO3−) activates the C[BOND]H bonds of alkanes and alcohols by a hydrogen-atom abstraction mechanism. The catalytic oxidation of these species is proposed to occur through a nonheme iron(V) oxo species, with a high reactivity in oxidation reactions (see picture).

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