Communication

Cryo Electron Tomography Reveals Confined Complex Morphologies of Tripeptide-Containing Amphiphilic Double-Comb Diblock Copolymers†

  1. Alison L. Parry Dr.1,
  2. Paul H. H. Bomans2,
  3. Simon J. Holder Dr.1,
  4. Nico A. J. M. Sommerdijk Dr.2,
  5. Stefano C. G. Biagini Dr.1

Article first published online: 11 SEP 2008

DOI: 10.1002/anie.200802834

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 47, Issue 46, pages 8859–8862, November 3, 2008

Additional Information

How to Cite

Parry, Alison L., Bomans, Paul H. H., Holder, Simon J., Sommerdijk, Nico A. J. M. and Biagini, Stefano C. G. (2008), Cryo Electron Tomography Reveals Confined Complex Morphologies of Tripeptide-Containing Amphiphilic Double-Comb Diblock Copolymers. Angew. Chem. Int. Ed., 47: 8859–8862. doi: 10.1002/anie.200802834

Author Information

  1. 1

    Functional Materials Group, Chemical Laboratory, School of Physical Sciences, University of Kent at Canterbury, Canterbury, Kent, CT2 7NR (UK), Fax: (+44) 1227-827-558

  2. 2

    Laboratory of Materials and Interface Chemistry and Soft Matter Cryo-TEM Research Unit, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven (The Netherlands)

  1. †

    We thank Dr. K. Lyakhova for valuable discussions.

Publication History

  1. Issue published online: 28 OCT 2008
  2. Article first published online: 11 SEP 2008
  3. Manuscript Received: 15 JUN 2008

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Keywords:

  • aggregation;
  • branching;
  • electron microscopy;
  • polynorbornene;
  • self-assembly
Thumbnail image of graphical abstract

Sequence sets structure: Amphiphilic norbornene-based double-comb diblock polymers with peptide and oligo(ethylene oxide) side chains aggregate in water to form unprecedented complex morphologies depending on the amino acid sequence of the peptide. The internal structures of the aggregates observed by cryo electron tomography show densely folded and highly branched wormlike micelles (left) and spherical aggregates with a bicontinuous architecture (right).

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