We thank Dr. K. Lyakhova for valuable discussions.
Cryo Electron Tomography Reveals Confined Complex Morphologies of Tripeptide-Containing Amphiphilic Double-Comb Diblock Copolymers†
Article first published online: 11 SEP 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 47, Issue 46, pages 8859–8862, November 3, 2008
How to Cite
Parry, Alison L., Bomans, Paul H. H., Holder, Simon J., Sommerdijk, Nico A. J. M. and Biagini, Stefano C. G. (2008), Cryo Electron Tomography Reveals Confined Complex Morphologies of Tripeptide-Containing Amphiphilic Double-Comb Diblock Copolymers. Angew. Chem. Int. Ed., 47: 8859–8862. doi: 10.1002/anie.200802834
- Issue published online: 28 OCT 2008
- Article first published online: 11 SEP 2008
- Manuscript Received: 15 JUN 2008
- electron microscopy;
Sequence sets structure: Amphiphilic norbornene-based double-comb diblock polymers with peptide and oligo(ethylene oxide) side chains aggregate in water to form unprecedented complex morphologies depending on the amino acid sequence of the peptide. The internal structures of the aggregates observed by cryo electron tomography show densely folded and highly branched wormlike micelles (left) and spherical aggregates with a bicontinuous architecture (right).