Surfactant-Assisted Synthesis of Nanoscale Gadolinium Metal–Organic Frameworks for Potential Multimodal Imaging


  • We acknowledge financial support from NSF and NCI. We thank W. J. Rieter and Dr. L. Ma for experimental help.


original image

Less basic: By controlling the pH value of the reaction medium, two different gadolinium-containing nanoscale metal–organic frameworks (NMOFs) based on the same building blocks can be synthesized (see picture). The NMOFs carry a large payload of Gd3+ centers and are efficient contrast agents for T2-weighted magnetic resonance imaging. The NMOFs are highly luminescent when doped with other lanthanide ions such as Eu and Tb.