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Keywords:

  • contrast agents;
  • magnetic resonance imaging;
  • metal–organic frameworks;
  • nanoparticles;
  • optical imaging
Thumbnail image of graphical abstract

Less basic: By controlling the pH value of the reaction medium, two different gadolinium-containing nanoscale metal–organic frameworks (NMOFs) based on the same building blocks can be synthesized (see picture). The NMOFs carry a large payload of Gd3+ centers and are efficient contrast agents for T2-weighted magnetic resonance imaging. The NMOFs are highly luminescent when doped with other lanthanide ions such as Eu and Tb.