We acknowledge financial support from NSF and NCI. We thank W. J. Rieter and Dr. L. Ma for experimental help.
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Communication
Surfactant-Assisted Synthesis of Nanoscale Gadolinium Metal–Organic Frameworks for Potential Multimodal Imaging†
Article first published online: 2 SEP 2008
DOI: 10.1002/anie.200802911
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue
1521-3773/asset/cover.gif?v=1&s=412bc65bdcb3f0e34a94f27c1c13e908726694d4 "Angewandte Chemie International Edition")
Angewandte Chemie International Edition
Volume 47, Issue 40, pages 7722–7725, September 22, 2008
Additional Information
How to Cite
Taylor, Kathryn M. L., Jin, A. and Lin, W. (2008), Surfactant-Assisted Synthesis of Nanoscale Gadolinium Metal–Organic Frameworks for Potential Multimodal Imaging. Angew. Chem. Int. Ed., 47: 7722–7725. doi: 10.1002/anie.200802911
- †
Publication History
- Issue published online: 22 SEP 2008
- Article first published online: 2 SEP 2008
- Manuscript Received: 18 JUN 2008
Funded by
- NSF
- NCI
Keywords:
- contrast agents;
- magnetic resonance imaging;
- metal–organic frameworks;
- nanoparticles;
- optical imaging
Less basic: By controlling the pH value of the reaction medium, two different gadolinium-containing nanoscale metal–organic frameworks (NMOFs) based on the same building blocks can be synthesized (see picture). The NMOFs carry a large payload of Gd3+ centers and are efficient contrast agents for T2-weighted magnetic resonance imaging. The NMOFs are highly luminescent when doped with other lanthanide ions such as Eu and Tb.